District 16-5A, arguably one of the toughest leagues in the state regardless of classification, opened last week to a couple of interesting results.

This Friday's only matchup in the district featuring winners from last week will take center stage, and could go a long way in determining 16-5A's playoff representatives come November.

Nacogdoches (4-0, 1-0) vs. Ennis (2-2, 1-0) is the ETSN.fm/Dairy Queen Game of the Week. Kickoff is set for 7:30 p.m. Friday from Ennis' Lion Memorial Stadium.

Last week, Nacogdoches sent shockwaves through the rest of the district with a 38-35 upset of arch-rival and No. 2 Lufkin -- the second consecutive season the Dragons have handed their biggest nemesis a loss.

Ennis, meanwhile, got district started on the right foot with a 42-24 victory at previously-unbeaten Jacksonville last Friday night at the Tomato Bowl.

In addition to having potential district-championship implications, Friday's clash could also have a large impact on seeding for the playoffs since both Ennis and Nacogdoches would most likely participate in the 5A Division II bracket.

Nacogdoches is led offensively by quarterback Hunter McClellan, running back Coronado Tolbert and a deep corps of receivers. The defense is spear-headed by the sibling tandem of senior cornerback/safety Jaylon Lane, an Oklahoma State commit, and junior safety Corey Lane.

Ennis, whose two losses came to state-ranked Mansfield Timberview and Denton Guyer, was a Class 4A Division II state semifinalist from a season ago. The Lions will be led by quarterback Devin Smith, the rushing duo of Taylor Thompson and Tre Elliott, and senior defensive end James Lockhart, a Texas A&M commit.

Be sure to check out the Nacogdoches-Ennis game preview Wednesday morning on ETSN.fm, follow staff writer Mike Graham (@Mike_ETSN) for updates throughout the game, and head back to ETSN.fm late Friday night or early Saturday morning for complete game coverage.